The control banding tool should be an integral part of the overall system of health and safety management at work established by the employer. It requires input data, irrespective of the phase of the nanomaterial’s life cycle, such as information collected at the work station through observation of actual work, toxicology data, etc. The output data generated by the control banding process will have an impact on other processes of the overall management system defined by the employer.

The purpose of this guidance note is to guide policy makers on the use of CBA for policy proposals. It includes the following topics: risk analysis, cost-benefit analysis, assessments of compliance costs, assessments of competition effects, and consultation. The cost-benefit analysis (CBA) is an analytical tool that can be used to measure the economic and social impact of government action by reference to the 'net social benefits' that action might produce. BCA is a power analytical tool that can aid in decision making.
 

CENARIOS® (Certifiable Nanospecific Risk Management and Monitoring System) enables identification, analysis and assessment of the potential risks and opportunities involved in nanotechnology and their possible impacts on people.

The ConsExpo nano tool can be used to estimate inhalation exposure to nanomaterials in consumer spray products. To run the model, user input on different exposure determinants such as the product and its use, the nanomaterial and the environmental conditions is required. Exposure is presented in different measures. The outcome of the assessment is an alveolar load in the lungs as one of the most critical determinants of inflammation of the lungs is both the magnitude and duration of the alveolar load of a nanomaterial.

To assess risks associated with nanotechnology operations. The tool estimates an emission probability and severity band and provides advice on what engineering controls to use. It includes nine domains covering handling of liquids, powders and abrasion of solids. Combines hazard “severity” scores and exposure “probability” scores in a matrix to obtain a level of risk and associated controls out of 4 possible levels of increasing risk and associated controls.

This document provides technical guidance on how to undertake socio-economic analysis (SEA) as part of a proposal to restrict the manufacturing, placing on the market and/or use of a substance in accordance with Article 69 of REACH.

This guidance is directed to registrant(s) who have identified several nanoforms of the same substance3 and need either to determine to which forms (including non-nanoforms) the available hazard data will be applicable and/or to design a testing strategy to fulfil the information requirements for the substance.

The model is very useful for the exposure assessment of products containing nanomaterials during shredding (end-of-life), a part of the life cycle where there is little data available. With a Bayesian probabilistic nature in its core, it uses subjective judgement when data is unavailable or scarce while being able to adapt and update risk forecasts as new information becomes available. Its novelty lies on a simplistic approach which combines the material and process variables of the system to determine the probability of number, size, mass and composition of released particles.

The Golden Egg Check is an online software tool to shape ideas into business cases and to attract funding from investors. Golden Egg Check is used by thousands of innovators within corporate, startup and scale-up companies and their supporters like incubators, educators, and investors and other funding programs.

This tool will help with the assessment and mitigation of nano-enabled product risks on human and environmental health. Using this tool, industry will be able to develop innovative methodologies to evaluate and manage human and environmental health risks of nano-enabled products, considering the whole product life cycle.  

The HIA under REACH includes a comprehensive narrative description of all the expected changes or impacts:

This tool helps researchers to identify, develop and validate product and business ideas with the help of modern business tools such as the Lean Business Model Canvas. While formulating their business case, researchers perform a Safety and Society Check as part of the Lean Business Canvas, as applied within the NanoNextNL Valorisation Programme. Risk levels for safety and society are indicated with arrows based on expertise of business case owners and an independent expert; left for safety and right for society.

The main goal of LICARA is to develop a structured life cycle approach for nanomaterials which enables the evaluation of the benefits and risks qualitatively with low and manageable efforts, over the nanoproduct's life time. It further allows a comparison with the risks and benefits of the conventional (non-nano) poducts. The tool stimulates economic, environmental and social opportunities. This tool is specifically intended for use by SME's to support them in communicating with regulators, and potential clients and investors.  

Grouping and read-across applications for the risk assessment of  nanomaterials have been described within the broader perspective of the MARINA risk assessment strategy. (http://www.mdpi.com/1660-4601/12/10/13415 )

This is a framework for reliability and relevance evaluation of ecotoxicity data for nanomaterials. The nanoCRED evaluation criteria, and accompanying guidance, were developed to be used in combination with those developed through the ‘Criteria for Reporting and Evaluating Ecotoxicity Data (CRED)’ project. This approach can accommodate all types of nanomaterials, all types of aquatic ecotoxicity studies, and qualitative as well as quantitative data evaluation requirements.

The NanoFASE model system will perform more complex, spatially-explicit simulations at smaller scales. It will simulate geographical area(s) as a network of cells. Within each cell, "reactors" will be linked by transport functions (e.g. sedimentation, deposition, effluent release, soil runoff, biota uptake). Implementation of material flow among cells (e.g. water flow, air movement) will enable multimedia transport modelling and fate prediction.

Designed originally as a research tool, SimpleBox4Nano has proven most useful in dedicated environmental fate studies, focused at understanding and predicting environmental fate from fundamental physical and chemical substance properties. Screening-level quantitative model, expresses NP transport and concentrations in and across air, rain, surface waters, soil, and sediment, accounting for nano-specific processes such as aggregation, attachment, and dissolution.

Screening tool for evaluation of exposure and hazard of NPs contained in products for professional and private use. To categorize and rank the possible exposure and hazards associated with a nanomaterial in a product. The primary focus was on nanomaterials relevant for professional end-users and consumers  as well as nanomaterials released into the environment.

Online control banding and risk management tool for manufactured nanomaterials. Hazard assessment and case-specific exposure potentials are combined into an integrated assessment of risk levels expressed in control bands with associated risk management recommendations. It can also be used to assess and manage emissions from nanoparticle-forming processes. Uses data on material properties, processes and production facilities to estimate occupational risk. The tool uses the Risk Quotient (i.e. the ratio of an exposure dose to a human effect threshold) to estimate risk deterministically.

Unknown when tool will be available

Authors conclude that one measurement device is appropriate and sufficient for a screening assessment of workplace exposure to NP for events with NP concentrations orders of magnitude higher than the backgrond concentration and workplaces with good air mixing conditions.

This experimental tool is used to explore the sentiments/uncertainties of involved stakeholders and is under construction. The idea behind a societal incubator is how to connect safe and responsible use to innovation and engineering. Within NanoNextNL the idea of a societal incubator explores the benefits and applicability of an equivalent of a business incubator, combined with the value of open dialogues and participants eager to give shape to Safe-by-Design.

Web-based Control Banding Tool using an Exposure Process Model. To assess health risks qualitatively after exposure to synthetic NPs. It concerns single particles as well as agglomerates or aggregates and applies to NPs.

Allows to estimate 'nanospecific risk potentials'  for synthetic nanomaterials and applications for workers, consumers and environment. It also provides the basis for early decision-making for or against new projects.